• Chemical Name Sulprostone
  • CAS No. 60325-46-4
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1.What is the Sulprostone ?

Sulprostone is a metabolism resistant synthetic analog of PGE2. It is a selective agonist for EP3 receptors with a Ki value of 0.35 nM at the human recombinant EP3-III receptor and an IC50 of 0.01 μM for the inhibition of PGE2 binding. Sulprostone is a potent stimulator of uterine smooth muscle contractions with high abortifacient activity.

2.What is the CAS number for Sulprostone ?

The CAS number of Sulprostone is 60325-46-4.

3.What are another words for Sulprostone ?

Synonyms?for?Sulprostone 60325-46-4:5-Heptenamide,7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-butenyl]-5-oxocyclopentyl]-N-(methylsulfonyl)-,(5Z)- (9CI); 5-Heptenamide,7-[3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl]-N-(methylsulfonyl)-,[1R-[1a(Z),2b(1E,3R*),3a]]-; CP 34089; Nalador; SHB 286; Sulprostone; ZK 57671

4.What is Sulprostone (60325-46-4) used for?

Sulprostone is a selective agonist of the PGE2 receptor.

InChI:InChI=1/C23H31NO7S/c1-32(29,30)24-23(28)12-8-3-2-7-11-19-20(22(27)15-21(19)26)14-13-17(25)16-31-18-9-5-4-6-10-18/h2,4-7,9-10,13-14,17,19-20,22,25,27H,3,8,11-12,15-16H2,1H3,(H,24,28)/t17-,19-,20-,22-/m1/s1

Relevant articles related to Sulprostone:

Article

Source

PROSTANOIDS. XXIX. SELECTIVE OXIDATION OF 7α-HYDROXY-6β-HYDROXYMETHYLENE-2-OXABICYCLOOCTAN-3-ONE BISTRIMETHYLSILYL ETHER BY REAGENTS BASED ON CHROMIUM(VI) AS KEY STAGE IN SYNTHESIS OF SULPROSTONE

Tolstikov, G. A.,Adler, M. E.,Miftakhov, M. S.

, p. 1908 - 1914 (2007/10/02)

Substituted ω-pentanorprostaglandins

-

, (2008/06/13)

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